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Philip Drummer is a newly crowned physician fresh out of medical school. His surgical internship takes him to the prestigious Philadelphia General Hospital where he begins training under the famous Dr. Richard Knight. Dr. Knight is an old school cardiac surgeon whose interests include fast cars and beautiful women. Phil and his fellow classmates soon begin to experience the raw brutality of a one-year surgical internship. They quickly discover that the elder Dr. Knight is obsessed with a surgical mortality ranking that is published in the Philadelphia Chronicle every other year. This ranking compares Dr. Knight to all of the other cardiac surgeons in the region, and fuels his larger than life persona. Unfortunately for all, Dr. Knights patients begin to die at an alarming rate, causing his local aura to suffer. To complicate the matter Phil becomes intimately involved with the current mistress of Dr. Knight. A mistress who lives in an opulent world funded by the wealthy and distinguished Doctor Knight. Phil Drummer soon finds himself fighting for survival in the midst of his powerful mentors suddenly confused life. A mentor, who once swore to a Hippocratic oath, yet is inexplicably trying to cope with a series of deaths amid a crumbling reputation. For everyone involved at the Philadelphia General Hospital the situation rapidly becomes a matter of life and death - amid rising suspicions as to the exact cause of each fatal event.